STEPdb: Sub-cellular Topologies of E.coli Polypeptides.

Table: Structure of the Type three secretion system (T3SS) of Enteropathogenic E.coli (EPEC)  Export to Excel  Export to HTML  Export to XML  Export to CSV  

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Structure of the Type three secretion system (T3SS) of Enteropathogenic E.coli (EPEC)

T3SS system of pathogenic E.coli EPEC

Structural sub assembly of injectisome Subunit function/role Common name Sct... Protein EPEC
Translocators
Translocon pore protein
SctE
EspD
Translocators
Translocon pore protein
SctB
EspB
Translocators
Tip/filament protein
SctA
EspA
Needle
Needle component
SctF
EscF
OM ring
Secretin
SctC
EscC
OM-IM connector
Inner rod
SctI
EscI
IM ring
Lipoprotein ring component
SctJ
EscJ
IM ring
Major IM ring component
SctD
EscD
Export apparatus or Translocase
Translocase channel
SctR
EscR
Export apparatus or Translocase
Translocase channel
SctS
EscS
Export apparatus or Translocase
Translocase channel
SctT
EscT
Export apparatus or Translocase
Minor component, external to channel
SctU
EscU
Export apparatus or Translocase
Major component, external to channel
SctV
EscV
ATPase complex
External stator connecting ATPase and Cytoplasmic ring
SctL
EscL
ATPase complex
Hexameric ring-structure ATPase
SctN
EscN
ATPase complex
Central stalk, inserting in ATPase ring
SctO
EscO
Cytoplasmic ring
Component of 6 Pod assembly
SctQ
SepQ
Cytoplasmic ring
Connector of Pods with SctD
SctK
EscK
Gatekeeper
Gatekeeper/Affinity switch
SctW
SepL
Gatekeeper
Subunit 1 of SctW chaperone heterodimer
 
SepD
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Reference


(Portaliou et al., 2016)
Portaliou, A.G., Tsolis, K.C., Loos, M.S., Zorzini, V., and Economou, A. (2016). Type III Secretion: Building and Operating a Remarkable Nanomachine. Trends Biochem Sci 41, 175-189. PMID: 26520801

 

 ©2015 e. Economou Lab